Baseline Hepatitis B Virus Surface Antigen Titers in Childhood Predict the Risk of Advanced Liver Fibrosis in Adulthood
Journal
Clinical Gastroenterology and Hepatology
Journal Volume
21
Journal Issue
3
Pages
663 - 669.e1
Date Issued
2023-03
Abstract
Hepatitis B virus (HBV) surface antigen (HBsAg) is a marker of both HBV covalently closed circular DNA and integrated HBV genome, whereas the HBV core-related antigen (HBcrAg) indicates the transcriptional activity of covalently closed circular DNA. This study examined the relationship between HBsAg and HBcrAg titers in childhood and advanced fibrosis in adulthood.
Subjects
Covalently Closed Circular DNA; Hepatitis B Core-related Antigen; Hepatitis B Surface Antigen; Liver Stiffness Measurement; Transient Elastography
SDGs
Publisher
W.B. Saunders
Type
journal article