Susceptibility-weighted imaging using magnetic resonance Fast Imaging with Steady-state Precession (FISP) gradient-echo sequence
Date Issued
2015
Date
2015
Author(s)
Lai, Jia-Chin
Abstract
Susceptibility-weighted imaging (SWI) is now extensively used in clinical neural applications to enhance the depiction of vascular architecture. The traditional procedure of SWI uses the phase information from RF-spoiled gradient-echo (SPGR) sequence to calculate a phase mask for improving contrast of small venous vessels, which is subsequently applied to enhance contrast of the magnitude image. The aim of this study is to investigate potential benefits of using the fast imaging with steady-state free precession (FISP) sequence on SWI application, for its variety of image contrast and high SNR efficiency. To obtain a proper set of MR scan parameters, the numerical simulation were employed to evaluate the signal performance of this proposed FISP sequence. We also presented the comparison in image quality and contrast between the FISP images and a standard SPGR sequence for SWI. The images of FISP-SWI led to a reduction of noise level for all subjects and all regions. Thus, it showed higher image quality such as SNR and CNR in some iron-rich brain tissues in contrast to SPGR-SWI. In conclusion, we expect that this proposed FISP sequence would be a promising imaging probe for other advanced SWI applications, and, meanwhile, this work may contribute to the current developments of the steady-state free-precession (SSFP).
Subjects
Magnetic resonance imaging (MRI)
gradient-echo (GRE) sequence
Susceptibility-weighted imaging (SWI)
steady-state free precession (SSFP)
fast imaging with steady-state precession (FISP)
Type
thesis
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