Renal effects of water-soluble polyarylsulfonated C(60) in rats with an acute toxicity study
Journal
Fullerene Science and Technology
Journal Volume
5
Journal Issue
7
Pages
1387-1396
Date Issued
1997
Author(s)
Abstract
Abstract Acute toxicity study of water soluble C60 was conducted in young female rats with one dose intraperitoneal injection of C60 ((CH2)4S03Na)4–6. The preliminary results indicated its LD50 value as approximately 600 mg/kg. The compound induced a unique phagolysosome-overload nephropathy that may serve as a biological marker in toxicity screening test for a series of synthesized water-soluble fullerenes.
SDGs
Type
journal article