Cobalt oxide acicular nanorods with high sensitivity for the non-enzymatic detection of glucose
Journal
Biosensors and Bioelectronics
Journal Volume
27
Journal Issue
1
Pages
125-131
Date Issued
2011
Author(s)
Abstract
Acicular cobalt oxide nanorods (CoONRs) were prepared for the non-enzymatic detection of glucose, first by directly growing layered cobalt carbonate hydroxide (LCCH) on a conducting fluorine-doped tin oxide (FTO) substrate using a simple chemical bath deposition (CBD) technique and then by transforming the LCCH into CoONRs through pyrolysis. The composition and grain size of the films of LCCH and CoONRs were verified by X-ray diffraction (XRD); their morphologies were examined by scanning electron microscopic (SEM) and transmission electron microscopic (TEM) images. CoONRs showed high electrocatalytic activity for the electro-oxidation of glucose in alkaline media, and the activity was strongly influenced by NaOH concentration, annealing temperature of CoONRs, and thickness of CoONRs film. The pertinent sensor could be successfully used for the quantification of glucose by amperometric method. The sensing parameters include wide linear range up to 3.5mM, a high sensitivity of 571.8μA/(cm 2mM), and a remarkable low detection limit of 0.058μM. The CoONRs modified electrode exhibited a high selectivity for glucose in human serum, against ascorbic acid, uric acid, and acetaminophen. ? 2011 Elsevier B.V.
Subjects
Acicular nanorods; Chemical bath deposition; Cobalt oxide; Glucose sensor; Modified electrode; Non-enzymatic detection
SDGs
Other Subjects
Acicular nanorods; Chemical bath deposition; Cobalt oxide; Modified electrode; Non-enzymatic detection; Alkalinity; Chemical detection; Cobalt; Cracking (chemical); Fluorine; Glucose sensors; Ketones; Nanocomposites; Nanorods; Organic acids; Sensors; Tin; Tin oxides; X ray diffraction; Glucose; ascorbic acid; cobalt carbonate hydroxide; cobalt derivative; cobalt oxide acicular nanorod; fluoride; glucose; nanorod; oxide; paracetamol; sodium hydroxide; unclassified drug; uric acid; alkalinity; article; biosensor; carbohydrate analysis; catalysis; chemical modification; electrode; film; glucose blood level; glucose oxidation; pyrolysis; scanning electron microscopy; sensitivity analysis; temperature; thickness; transmission electron microscopy; X ray diffraction; Biosensing Techniques; Blood Glucose; Cobalt; Diabetes Mellitus; Fluorine; Humans; Limit of Detection; Nanotubes; Oxides; Sensitivity and Specificity; Tin Compounds; X-Ray Diffraction
Type
journal article