Publication:
An integrated microcantilever-based wireless DNA chip for Hepatitis B Virus (HBV) DNA detection

cris.virtual.departmentInternal Medicineen_US
cris.virtual.departmentInternal Medicine-NTUHen_US
cris.virtual.orcid0000-0003-3790-484Xen_US
cris.virtualsource.department57f081cd-f1b7-4226-a934-6fb68cc0b214
cris.virtualsource.department57f081cd-f1b7-4226-a934-6fb68cc0b214
cris.virtualsource.orcid57f081cd-f1b7-4226-a934-6fb68cc0b214
dc.contributor.authorHuang C.-W.en_US
dc.contributor.authorHuang Y.-J.en_US
dc.contributor.authorLin T.-H.en_US
dc.contributor.authorLin C.-T.en_US
dc.contributor.authorJEN-KUANG LEEen_US
dc.contributor.authorChen L.-G.en_US
dc.contributor.authorHsiao P.-Y.en_US
dc.contributor.authorWu B.-R.en_US
dc.contributor.authorHsueh H.-T.en_US
dc.contributor.authorKuo B.-J.en_US
dc.contributor.authorTsai H.-H.en_US
dc.contributor.authorLiao H.-H.en_US
dc.contributor.authorJuang Y.-Z.en_US
dc.contributor.authorLu S.-S.en_US
dc.date.accessioned2022-03-07T07:05:58Z
dc.date.available2022-03-07T07:05:58Z
dc.date.issued2011
dc.description.abstractAn integrated DNA detection system-on-chip (SoC), which includes microcantilever based DNA sensors, readout circuits, MCU, and RF OOK TX/RX, is implemented by a 0.35μm CMOS Bio-MEMS process and post-processing steps. For DNA sensing, the DNA immobilization process is used to make the probe DNA attaches on the surface of microcantilever via sulfur-gold covalent bond. Then the biosensor is proved to be sensitive to surface stress change induced by DNA hybridization on the surface of the microcantilever. The experiment results reveal the developed DNA detection SoC has excellent selectivity and detection concentration range of the specific DNA from 1pM to 10nM. Copyright ? (2011) by the Chemical and Biological Microsystems Society.
dc.identifier.issn#VALUE!
dc.identifier.scopus2-s2.0-84883762427
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84883762427&partnerID=40&md5=17b030bdd28994715ecacc51c3c82dbf
dc.identifier.urihttps://scholars.lib.ntu.edu.tw/handle/123456789/596635
dc.relation.ispartof15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
dc.relation.journalvolume2
dc.relation.pages984-986
dc.subject.classification[SDGs]SDG3
dc.subject.otherConcentration ranges; DNA hybridization; DNA immobilization; Hepatitis B virus; Micro-cantilevers; Post processing; Read-out circuit; SoC; Application specific integrated circuits; Composite micromechanics; Programmable logic controllers; Viruses; DNA
dc.titleAn integrated microcantilever-based wireless DNA chip for Hepatitis B Virus (HBV) DNA detectionen_US
dc.typeconference paper
dspace.entity.typePublication

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