海洋天然藥物開發研究(總計畫)
Date Issued
2003-07-31
Date
2003-07-31
Author(s)
DOI
912323B002008
Abstract
The integrated project was designed to explore bioactive nature products from marine
microalgae, macroalgae and soft corals indigenous to Taiwan. One hundred and fifty three
samples of macroalgae and 54 soft corals samples were collected, and more than 200 strains of
microalgae were isolated and cultivated in the first year. In the previous screening, more than 20
% of the samples mentioned above were found to exert strong cytotoxicity. After that, twenty-six
compounds were purified from microalgae, at least 6 of them exerted strong cytotoxicity, and 12
of them were new compounds, among which 2 new skeletal compounds were found. Fifty-five
compounds were purified from macroalgae, nine of them exerted strong cytotoxicity, and 28 of
them were new compounds, among which 14 new skeletal compounds were found. Eight-five
compounds were purified from soft corals, eleven of them exerted strong cytotoxicity, thirty-five
of them were new compounds, among which 2 new skeletal compounds were found, revealing
the potential to approach the bioactive or new compounds from these marine creatures indigenous
to Taiwan.
Subjects
nature products
soft corals
microalgae
macroalgae
SDGs
Publisher
臺北市:國立臺灣大學漁業科學研究所
Type
journal article
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