A noninvasive evaluation analysis of amniotic fluid embolism and disseminated intravascular coagulopathy
Journal
Journal of Maternal-Fetal and Neonatal Medicine
Journal Volume
24
Journal Issue
11
Pages
1411-1415
Date Issued
2011
Author(s)
Liao, W.-C.
Abstract
Objective. Amniotic fluid embolism (AFE) is a complication of pregnancy with a high mortality rate. The diagnosis of AFE is currently based on clinical findings, acute respiratory distress, cardiovascular collapse during labor and delivery, and immediate massive postpartum hemorrhaging. The serum biological markers are unreliable, and their detection requires a long time intervals for result. An early diagnosis is very important and prompts the clinical management of the condition. Study design and results.We present here a noninvasive method (time frequency, entropy) to analyze heart rate variability (HRV). 3D-Spectrogram and entropy were derived from the RR interval of two pregnant subjects with AFE and disseminated intravascular coagulation (DIC) survived after delivering normal babies admitted to the Taiwan Seventh-day Adventists Hospital, and the entropy values were compared with those of 105 healthy pregnant subjects in the same hospital. Conclusions. We show that these methods can be successfully applied to the diagnosis of AFE and predict the prognosis of DIC. We also show that CT scans can be applied to the diagnosis of pulmonary embolism, eliminating the need to pathology. ? 2010 Informa UK, Ltd.
Subjects
Amniotic fluid embolism; disseminated intravascular coagulation; heart rate variability; Hilbert-Huang transform; Short-time Fourier Transform
SDGs
Other Subjects
recombinant blood clotting factor 7a; abdominal hysterectomy; adult; amnion fluid embolism; article; asystole; blood oxygen tension; blood pressure measurement; blood transfusion; case report; computer assisted tomography; controlled study; cyanosis; disseminated intravascular clotting; dyspnea; electrocardiography; entropy; female; frequency analysis; heart rate variability; heart ventricle fibrillation; hemoglobin determination; human; immunohistochemistry; lung embolism; non invasive procedure; partial thromboplastin time; postpartum hemorrhage; priority journal; prognosis; prothrombin time; pulse rate; Adult; Disseminated Intravascular Coagulation; Electrocardiography; Embolism, Amniotic Fluid; Female; Heart Rate; Humans; Hysterectomy; Postpartum Hemorrhage; Pregnancy; Pregnancy Outcome; Tomography, X-Ray Computed
Type
journal article