Application of Solid-Phase Microextraction on Determining Airborne Formaldehyde
Date Issued
2005
Date
2005
Author(s)
Liou, Siou-Wun
DOI
zh-TW
Abstract
Formaldehyde is a high reactive compound commonly used in industry and medical treatment. Exposure to formaldehyde results in acute effect on upper respiratory tract and possible carcinogeness. In this study, formaldehyde was sampled by derivation with o-(2, 3, 4, 5, 6 pentafluorobenzyl)-hydroxylamine hydrochloride (PFBHA) coated on 65 μm of poly (dimethylsiloxane)/divinylbenzene solid-phase microextraction fibers. Two types of sampling mode, fiber extruded outside the needle and fiber retracted inside the needle, were carried out. A standard gas generation system regulated the concentration of formaldehyde, temperature and humidity in an exposure chamber. A kind of Chinese incense was burned in incense combustion system where flow rate was regulated at 3Lpm. The NIOSH-2451 active sampling method with XAD-2 was used for validation of the SPME method. To sample analytes, thermal desorption incorporated with gas chromatography with flame ionization detector was used.
The amount of formaldehyde collected on fibers, either in extruded mode or retracted mode, is well correlated with the concentration of formaldehyde and sampling time. Temperature (15°C-35°C) and humidity (25%-80%) did not significantly affect the performance of the retracted fibers, but did affect that performance of the extruded fibers. The variation of sampling rate was mainly attributed to temperature by 68.91% and humidity by 19.63% while fibers were used in the extruded mode. And when the fiber was used in the retracted mode, concentration (36.28%) and sampling time (27.89%) both attributed to the variation of sampling rate.
To sample incense smoke, the amount of formaldehyde collected by the extruded fibers without prefiltration was higher than that with prefiltration. The relationship between mass and sampling time was nonlinear for the samples without prefiltration, but it was linear for the samples with prefiltration. Besides, compounds collected in the former were more complicate. It suggests that compounds in addition to particulate–bonded formaldehyde from burning Chinese incense would be sampled by the PFBHA coated PDMS/DVB fiber.
Subjects
五氟芐羥胺[o-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine hydrochloride (PFBHA)]
甲醛
拜香
固相微萃取
Poly (dimethysiloxane)-divinylbenzene (PDMS-DVB)
o-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine hydrochloride (PFBHA)]
formaldehyde
incense
solid-phase microextraction (SPME)
Poly (dimethylsiloxane)-divinylbenzene (PDMS-DVB)
Type
thesis
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