Pemetrexed in combination with cisplatin versus cisplatin monotherapy in East Asian patients with recurrent or metastatic head and neck cancer: Results of an exploratory subgroup analysis of a phase III trial
Journal
Asia-Pacific Journal of Clinical Oncology
Journal Volume
9
Journal Issue
4
Pages
331-341
Date Issued
2013
Author(s)
Abstract
Aim: An exploratory subgroup analysis of East Asian (EA) patients in a phase III trial was conducted to assess efficacy and safety trends based on ethnicity. Methods
Subjects
Cisplatin; Clinical trial; Head and neck neoplasm; Pemetrexed; Phase III
SDGs
Other Subjects
cisplatin; pemetrexed; placebo; antineoplastic agent; cisplatin; glutamic acid derivative; guanine; pemetrexed; adult; aged; anemia; anorexia; article; cancer prognosis; China; combination chemotherapy; controlled study; diarrhea; double blind procedure; drug efficacy; drug safety; drug withdrawal; ethnicity; fatigue; febrile neutropenia; female; head and neck squamous cell carcinoma; human; kidney failure; Korea; leukopenia; major clinical study; male; metastasis; monotherapy; multiple cycle treatment; nausea and vomiting; neutropenia; overall survival; phase 3 clinical trial; priority journal; progression free survival; randomized controlled trial; recurrent cancer; Taiwan; thrombocytopenia; treatment response; analogs and derivatives; Asian continental ancestry group; Carcinoma, Squamous Cell; clinical trial; ethnology; Head and Neck Neoplasms; middle aged; Neoplasm Recurrence, Local; survival; treatment outcome; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asian Continental Ancestry Group; Carcinoma, Squamous Cell; Cisplatin; Double-Blind Method; Female; Glutamates; Guanine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Treatment Outcome
Type
journal article