Motion of cancer-cell lamellipodia perturbed by laser light of two wavelengths

We employ 405 and 1064 nm laser light to perturb the motions of lung cancer cell lamellipodia. The 405 nm light causes lamellipodial retractions while the 1064 nm light enhances protrusions. With the observation of actin distributions in the lamellipodia, we find that the 1064 nm laser light increases the density of actin near the illuminated site, while the 405 nm light reduces the actin distribution. ? 2010 American Institute of Physics.