In vivo antioxidant activities of the essential oils and their constituents from leaves of the Taiwanese Cinnamomum osmophloeum
Journal
Journal of Agricultural and Food Chemistry
Journal Volume
60
Journal Issue
12
Pages
3092-3097
Date Issued
2012
Author(s)
Hsu, Fu-Lan
Li, Wen-Hsuan
Yu, Chan-Wei
Hsieh, Yi-Chen
Yang, Ying-Fei
Liu, Jui-Tung
Shih, Justin
Chu, Yu-Ju
Yen, Pei-Ling
Abstract
Cinnamomum osmophloeum Kaneh is an indigenous tree species in Taiwan. In this study, phytochemical characteristics and antioxidant activities of the essential oils and key constituents from the leaves of two C. osmophloeum clones were investigated. The two trees possess two chemotypes, which were classified as the cinnamaldehyde type and camphor type. We demonstrated that the essential oils from C. osmophloeum leaves exerted in vivo antioxidant activities in Caenorhabditis elegans. In addition, trans-cinnamaldehyde and D-(+)-camphor, which respectively represent the major compounds in the cinnamaldehyde-type and camphor-type trees, exerted significant in vivo antioxidant activities against juglone-induced oxidative stress in C. elegans. Moreover, expressions of antioxidative-related genes, including superoxide dismutase (SOD) and glutathione S-transferase (GST), were significantly induced by trans-cinnamaldehyde and D-(+)-camphor from C. osmophloeum leaves. Our results showed that the essential oils from C. osmophloeum leaves and their major compounds might have good potential for further development as nutraceuticals or antioxidant remedies.
Type
journal article