Factor of Risk for Hip Fracture in Normal Chinese Men and Women in Taiwan
Resource
CALCIFIED TISSUE INTERNATIONAL v.65 n.6 pp.422-426
Journal
CALCIFIED TISSUE INTERNATIONAL
Journal Volume
v.65
Journal Issue
n.6
Pages
422-426
Date Issued
1999
Date
1999
Author(s)
YANG, RONG-SEN
LIU, TANG-KUE
HANG, YI- SHIONG
CHIENG, POON-UNG
TSAI, KEH-SUNG
Abstract
We have investigated the age-related change in factor of risk (Phi) for the proximal femoral load during free fall in 548 females and 240 males aged 21-79 years. These individuals were divided into either young (age<50 years) or old group (age >/=50 years). Another 26 females with hip fractures were included for comparison. The bone mineral density (BMD) of proximal femoral neck was measured by a Norland XR-26 dual-energy X-ray absorptiometer (DXA). The estimated fracture load (L) of femoral neck was calculated from the BMD with the regression equation derived by Courtney et al. [2,3] and estimated fall force (F) by body weight and height according to the regression equation derived by Nakamura et al. [6] respectively. Phi was defined as the quotient of F/L. The results showed an age-related decrease of BMD (P < 0.001) in both genders corrected for weight and height. By multiple linear regression analysis, the F decreased significantly with aging corrected for BMD in old males(partial r = -0. 255, P < 0.01) and increased with aging in all females(young, partial r=0. 287, p < 0.001; old, partial r = 0.252, P < 0.001). L decreased significantly with aging corrected for height and weight in males (young, partial r = -0.401, P < 0.01; old, partial r = -0.178, P < 0.05) and females (young, partial r = -0. 168, P < 0.05; old, partial r =-0.459, P < 0.001). However Phi decreased with aging in young males (P < 0.01) and females ( young: P < 0.001, old: P < 0.001). Phi increased in old women but not in old men, and was higher in old women compared with old men. The 26 patients with hip fractures had a significantly higher Phi value than 85 age-matched women. In conclusion, Phi may provide a comprehensive comparison of the risk of hip fracture in the elderly population.
Subjects
factor of risk (Φ)
Hip fracture
Chinese
Bone mineral density
Bone area