Influence of the Timing of Leptomeningeal Metastasis on the Outcome of EGFR-Mutant Lung Adenocarcinoma Patients and Predictors of Detectable EGFR Mutations in Cerebrospinal Fluid
Journal
Cancers
Journal Volume
14
Journal Issue
12
Date Issued
2022-06-07
Author(s)
Liao, Pei-Ya
Ou, Wei-Fan
Sun, Ming-Hsi
Huang, Chih-Mei
Chen, Kun-Chieh
Hsu, Kuo-Hsuan
Huang, Yen-Hsiang
Tseng, Jeng-Sen
Yang, Tsung-Ying
Chang, Gee-Chen
Abstract
We aim to evaluate the influence of the timing of leptomeningeal metastasis (LM) occurrence on the outcome of EGFR-mutant lung adenocarcinoma and to explore the predictors of detectable EGFR mutation in the cerebrospinal fluid (CSF).
Subjects
cerebrospinal fluid (CSF); epidermal growth factor receptor (EGFR); leptomeningeal metastasis; lung adenocarcinoma
Publisher
MDPI
Type
journal article