New cytotoxic steroids from the soft coral Clavularia viridis
Resource
Steroids 72 (6-7): 573-579
Journal
Steroids
Journal Volume
72
Journal Issue
6-7
Pages
573-579
Date Issued
2007
Author(s)
Abstract
Ten new cytotoxic steroids, stoloniferones H-Q (1-10) were isolated from the methylene chloride solubles of the soft coral Clavularia viridis. The structures of the metabolites were elucidated on the basis of spectroscopic (IR, MS, and 1D and 2D NMR) analysis and their cytotoxicity against selected cancer cells was measured in vitro. ? 2007 Elsevier Inc. All rights reserved.
Subjects
Clavularia viridis; Cytotoxicity; Steroids
Other Subjects
cytotoxic agent; dichloromethane; steroid; stoloniferone h; stoloniferone i; stoloniferone j; stoloniferone k; stoloniferone l; stoloniferone m; stoloniferone n; stoloniferone o; stoloniferone p; stoloniferone q; unclassified drug; animal cell; animal experiment; article; cancer cell; chemical structure; Cluvaria viridis; drug isolation; drug mechanism; human; human cell; in vitro study; infrared spectrometry; intermethod comparison; marine species; mass spectrometry; metabolite; nonhuman; nuclear magnetic resonance spectroscopy; Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Humans; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Steroids; Alcyonacea; Clavularia viridis
Type
journal article
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