Novel Polyhydroxysteroids from the Formosan Soft Coral Sarcophyton glaucum
Resource
Journal of the Chinese Chemical Society 51 (1): 217-220
Journal
Journal of the Chinese Chemical Society
Journal Volume
51
Journal Issue
1
Pages
217-220
Date Issued
2004
Date
2004
Author(s)
Abstract
Two novel polyhydroxysteroids, (24S)-24-methylcholestane-3β,5α, 6β,25ξ,26-pentol 26-n-decanoate (1), (24S)-24-methylcholestane-3β, 5α,6β,25ξ,26-pentol 25,26-diacetate (2), and three known sterols (3-5), have been isolated from a Formosan soft coral Sarcophyton glaucum. The molecular structures of these compounds were determined by spectral methods. The cytotoxicity of these compounds toward various cancer cell lines has also been determined.
Subjects
Cytotoxicity; Polyhydroxysteroids; Sarcophyton glaucum; Soft coral
SDGs
Other Subjects
24 methylcholestane 1beta,3beta,5alpha,6beta,25zeta pentol 25 monoacetate; 24 methylcholestane 3beta,5alpha,6beta,25zeta tetrol; 24 methylcholestane 3beta,5alpha,6beta,25zeta tetrol 25 monoacetate; 24 methylcholestane 3beta,5alpha,6beta,25zeta,26 pentol 25,26 diacetate; 24 methylcholestane 3beta,5alpha,6beta,25zeta,26 pentol 26 n decanoate; hydroxysteroid; unclassified drug; animal cell; animal model; antineoplastic activity; article; cancer cell culture; controlled study; coral; drug cytotoxicity; drug isolation; drug screening; leukemia P 388; mouse; nonhuman; nuclear magnetic resonance spectroscopy; sarcophyton glaucum
Type
journal article
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