角膜間質層角質細胞的自殺行為與角膜移植手術的關係
Date Issued
2000
Date
2000
Author(s)
王一中
DOI
892314B002247
Abstract
Several investigators have shown recently that anterior stromal keratocytes undergo
programmed cell death (apoptosis ) in response to corneal epithelial injury, and it is believed
that this phenomenon plays an important role in wound healing after many kinds of corneal
surgery such as photorefractive keratectomy (PRK). However, It is not known whether degree
of apoptosis may account for variations of wound healing observed after penetrating
keratoplasty (PKP). The purpose of this study is to investigate whether keratocyte apoptosis
takes place during storage and process period of donor cornea. New Zealand white rabbits are
used as the animal models. The result of this study showed that the way of preservation and
transportation will affect keratocyte apoptosis in corneal buttons.
programmed cell death (apoptosis ) in response to corneal epithelial injury, and it is believed
that this phenomenon plays an important role in wound healing after many kinds of corneal
surgery such as photorefractive keratectomy (PRK). However, It is not known whether degree
of apoptosis may account for variations of wound healing observed after penetrating
keratoplasty (PKP). The purpose of this study is to investigate whether keratocyte apoptosis
takes place during storage and process period of donor cornea. New Zealand white rabbits are
used as the animal models. The result of this study showed that the way of preservation and
transportation will affect keratocyte apoptosis in corneal buttons.
Subjects
cornea
keratocyte
apoptosis
penetrating keratoplasty
corneal epithelial cell
Publisher
臺北市:國立臺灣大學醫學院眼科
Type
journal article
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