Circulating Fibroblast Growth Factor-23 Levels Can Predict Rapid Kidney Function Decline in a Healthy Population: A Community-Based Study
Journal
Biomolecules
Journal Volume
13
Journal Issue
1
Date Issued
2023
Author(s)
Chen, Hsing-Yu
Fang, Wei-Ching
Chu, Shao-Chi
Wang, Po-Hsi
Lee, Chin-Chan
Wu, I-Wen
Sun, Chiao-Yin
Hsu, Heng-Jung
Chen, Chun-Yu
Chen, Yung-Chang
Pan, Heng-Chih
Abstract
Fibroblast growth factor-23 (FGF-23) associates with decreased kidney function in patients with chronic kidney disease (CKD). However, the correlation between circulating FGF-23 levels and the rate of renal function decline in healthy individuals is largely unknown. We aimed to evaluate the predictive performance of FGF-23 for rapid kidney function decline (RKFD) in a community-based study.
Subjects
FGF-23; biomarker; chronic kidney disease; rapid kidney function decline
SDGs
Publisher
MDPI
Type
journal article