Is elective neck dissection justified in cT2N0M0 oral cavity cancer defined according to the AJCC eighth edition staging system?
Journal
Cancer medicine
Journal Volume
13
Journal Issue
1
Date Issued
2024-01-03
Author(s)
Chen, Tsung-Ming
Terng, Shyuang-Der
Lee, Li-Yu
Lee, Shu-Ru
Ng, Shu-Hang
Kang, Chung-Jan
Lin, Jin-Ching
Chien, Chih-Yen
Hua, Chun-Hung
Chen, Wen-Cheng
Tsai, Yao-Te
Tsai, Chi-Ying
Lin, Chien-Yu
Fan, Kang-Hsing
Wang, Hung-Ming
Hsieh, Chia-Hsun
Yeh, Chih-Hua
Lin, Chih-Hung
Tsao, Chung-Kan
Cheng, Nai-Ming
Fang, Tuan-Jen
Huang, Shiang-Fu
Lee, Li-Ang
Fang, Ku-Hao
Wang, Yu-Chien
Lin, Wan-Ni
Hsin, Li-Jen
Yen, Tzu-Chen
Wen, Yu-Wen
Liao, Chun-Ta
Abstract
The current NCCN guidelines recommend considering elective neck dissection (END) for early-stage oral cavity squamous cell carcinoma (OCSCC) with a depth of invasion (DOI) exceeding 3 mm. However, this DOI threshold, determined by evaluating the occult lymph node metastatic rate, lacks robust supporting evidence regarding its impact on patient outcomes. In this nationwide study, we sought to explore the specific indications for END in patients diagnosed with OCSCC at stage cT2N0M0, as defined by the AJCC Eighth Edition staging criteria.
Subjects
cT2N0M0; cancer registry; clinical outcomes; elective neck dissection; occult lymph node metastasis; oral cavity squamous cell carcinoma
Type
journal article