Apamin does not inhibit human cardiac Na+ current, L-type Ca2+ current or other major K+ currents
Journal
PloS one
Journal Volume
9
Journal Issue
5
Pages
e96691
Date Issued
2014-05-05
Author(s)
Abstract
Apamin is commonly used as a small-conductance Ca2+-activated K+ (SK) current inhibitor. However, the specificity of apamin in cardiac tissues remains unclear.
Subjects
ACTIVATED POTASSIUM CHANNEL; SMALL-CONDUCTANCE; FUNCTIONAL ROLES; PULMONARY VEIN; QT SYNDROME; SK2; LOCALIZATION; TRAFFICKING; EXPRESSION; MUTATION
Publisher
PUBLIC LIBRARY SCIENCE
Type
journal article