Matrix-assisted laser desorption/ionization mechanism study with dihydroxybenzoic acid isomers as matrices
Resource
Rapid Communications in Mass Spectrometry 22 (2): 130 - 134
Journal
Rapid Communications in Mass Spectrometry
Pages
130-134
Date Issued
2008
Date
2008
Author(s)
Jessome, Lori
Hsu, Nien-Yeen
Wang, Yi-Sheng
Chen, Chung-Hsuan
Abstract
Desorption and ionization efficiencies of matrix-assisted laser desorption/ionization (MALDI) for various biomolecules with different dihydroxybenzoic acid isomers were studied. No clear relationships were observed between MALDI biomolecule signals vs. gas-phase basicity, proton affinity and ionization potential. This indicates the the gas-phase protonation mechanism is not adequate to explain the observed results.
SDGs
Type
journal article