Outcomes of malignant external otitis: Survival vs mortality
Journal
Acta Oto-Laryngologica
Journal Volume
130
Journal Issue
1
Pages
89-94
Date Issued
2010
Author(s)
Abstract
Conclusions. In patients with malignant external otitis (MEO), mortality was not related to age, sex, degree of glucose tolerance, duration of diabetes mellitus (DM), microorganism, comorbid disease, or involvement of a single cranial nerve. Severe complications such as skull base osteomyelitis, intracranial extension, and involvement of multiple cranial nerves were correlated with mortality. Objectives. To analyze the factors that affect the survival of patients with MEO in today's era of advanced antibiotics. Patients and methods. Patients with a diagnosis of MEO from 1993 to 2005 were collected. Results. A total 26 patients with a mean age of 63.7±10.2 years were included. All had a history of DM. Pseudomonas aeruginosa (26.9%), Klebsiella pneumoniae (19.2%), and fungus (15.4%) were most frequently found in pus cultures. Cranial nerves were involved in 11 patients: the facial nerve was most frequently (38.46%) involved. Complications such as osteomyelitis (11 patients) and intracranial involvement (3 patients) were noted in this series. Mastoidectomy was performed in 12 patients. A total of five patients died. ? 2010 Informa UK Ltd All rights reserved.
SDGs
Other Subjects
aminoglycoside; cephalosporin; penicillin G; quinolone; adult; aged; article; Aspergillus niger; bacterium culture; brain disease; cause of death; clinical article; comorbidity; computer assisted tomography; cranial nerve; cranial neuropathy; external otitis; facial nerve; female; human; Klebsiella pneumoniae; length of stay; male; malignant external otitis; mastoidectomy; mortality; osteomyelitis; priority journal; Pseudomonas aeruginosa; pus; skull base; survival time; treatment outcome; Cranial Nerve Diseases; Diabetes Complications; disease course; Klebsiella Infections; Klebsiella pneumoniae; middle aged; Mycoses; osteomyelitis; Otitis Externa; Pseudomonas aeruginosa; Pseudomonas Infections; retrospective study; risk factor; survival; Aged; Comorbidity; Cranial Nerve Diseases; Diabetes Complications; Disease Progression; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Length of Stay; Male; Middle Aged; Mycoses; Osteomyelitis; Otitis Externa; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Risk Factors; Skull Base; Survival Analysis
Publisher
Informa Healthcare
Type
journal article