Optically clear alginate hydrogels for spatially controlled cell entrapment and culture at microfluidic electrode surfaces
Journal
Lab on a Chip - Miniaturisation for Chemistry and Biology
Journal Volume
13
Journal Issue
10
Pages
1854-1858
Date Issued
2013
Author(s)
Betz, J.F.
Cheng, Y.
Tsao, C.-Y.
Zargar, A.
Wu, H.-C.
Luo, X.
Payne, G.F.
Bentley, W.E.
Rubloff, G.W.
Abstract
We describe an innovation in the immobilization, culture, and imaging of cells in calcium alginate within microfluidic devices. This technique allows unprecedented optical access to the entirety of the calcium alginate hydrogel, enabling observation of growth and behavior in a chemical and mechanical environment favored by many kinds of cells.
SDGs
Type
journal article