Recommended first-line management of brain metastases from melanoma: A multicenter survey of clinical practice
Journal
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Journal Volume
168
Pages
89
Date Issued
2022
Author(s)
Jablonska, Paola Anna
Fong, Chin Heng
Kruser, Timothy
Weiss, Jessica
Liu, Zhihui Amy
Takami, Hirokazu
Narita, Yoshitaka
Ynoe de Moraes, Fabio
Dasgupta, Archya
Ong, Choo Khoon
Pavlakis, Nicholas
Kongkham, Paul
Butler, Marcus
Shultz, David B
Abstract
Radiotherapy (RT) and surgery (Sx) are effective in treating brain metastases. However, immune checkpoint inhibitors (ICI) have shown activity against asymptomatic melanoma brain metastases (MBM). BRAF/MEK inhibitors can be used to treat BRAF V600 mutation positive (BRAF+) MBM.
Subjects
BRAF mutation; Brain metastases; Immunotherapy; Melanoma; Stereotactic radiosurgery
Publisher
ELSEVIER IRELAND LTD
Type
journal article