Determination of antibiotics in sludge
Journal
Chinese Journal of Environmental Engineering
Journal Volume
10
Journal Issue
2
Pages
985-991
Date Issued
2016
Author(s)
Abstract
Ultrasonic assisted extraction (USE), accelerated solvent extraction (ASE) and matrix solid-phase dispersion (MSPD) were applied to extract 10 antibiotics (sulfadiazine, sulfamethazine, sulfamerazine, sulfameter, sulfamethoxazole, sulfadimethoxine, enrofloxacin, sarafloxacin, danofloxacin, oxytetracycline) in the sludge. The antibiotic recoveries by MSPD were better compared to USE and ASE. In addition, MSPD was easy to operate, cost effective, and environmentally friendly. Thus, MSPD coupled with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was used to analyze the antibiotics in the sludge samples. Results show that the recoveries of the 10 antibiotics are in the range of 40.15%-114.73%, and the method detection limits are 0.02-0.28 μg/kg. Summer and winter sludge samples from a wastewater treatment plant of Xiamen were analyzed. The concentrations of 10 target antibiotics are nd-1013 μg/kg. Oxytetracycline and enrofloxacin are the predominant antibiotics in summer and winter samples, with the mean concentrations of 789.67 μg/kg and 32.65 μg/kg, respectively. © 2016, Science Press. All right reserved.
Subjects
Antibiotics; Determination; MSPD; Sludge
Type
journal article