Ovarian cancer risk score predicts chemo-response and outcome in epithelial ovarian carcinoma patients
Journal
Journal of gynecologic oncology
Journal Volume
32
Journal Issue
2
Date Issued
2021
Author(s)
Abstract
Cytoreductive surgery followed by adjuvant chemotherapy is a standard frontline treatment for epithelial ovarian cancer (EOC). We aimed to develop an ovarian cancer risk score (OVRS) based on the expression of 10 ovarian-cancer-related genes to predict the chemoresistance, and outcomes of EOC patients.
Subjects
Drug Resistance; Gene Analysis; Ovarian Cancer; Prognostic Factor; Risk Score
Other Subjects
CA 125 antigen; CA 19-9 antigen; carcinoembryonic antigen; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor; platinum complex; adult; Article; cancer prognosis; cancer staging; cancer survival; case control study; clinical decision making; clinical protocol; controlled study; cytoreductive surgery; data base; disease course; disease free survival; drug resistance; female; human; human tissue; major clinical study; middle aged; nuclear magnetic resonance imaging; outcome assessment; ovarian cancer risk score; ovary carcinoma; overall survival; quantitative analysis; real time polymerase chain reaction; receiver operating characteristic; risk assessment; scoring system; survival rate; drug resistance; genetics; ovary tumor; risk factor; Carcinoma, Ovarian Epithelial; Case-Control Studies; Drug Resistance, Neoplasm; Female; Humans; Ovarian Neoplasms; Risk Factors
Type
journal article