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  4. Transnasal esophagogastroduodenoscopy for evaluation of upper gastrointestinal non-neoplastic disorders in patients with fresh hypopharyngeal cancer
 
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Transnasal esophagogastroduodenoscopy for evaluation of upper gastrointestinal non-neoplastic disorders in patients with fresh hypopharyngeal cancer

Journal
Laryngoscope
Journal Volume
123
Journal Issue
4
Pages
975-979
Date Issued
2013
Author(s)
CHENG-PING WANG  
Hu Y.-L.
TSENG-CHENG CHEN  orcid-logo
PEI-JEN LOU  
TSUNG-LIN YANG  
PING-HUEI TSENG  
JENG-YUH KO  
TZU-YU HSIAO  
YI-CHIA LEE  
DOI
10.1002/lary.23726
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84875476612&doi=10.1002%2flary.23726&partnerID=40&md5=bf3f363cdeb0b783e674dd4a3edb8a11
https://scholars.lib.ntu.edu.tw/handle/123456789/518243
Abstract
Objectives/Hypothesis: Upper gastrointestinal (UGI) tract non-neoplastic disorders are detrimental to cancer treatment. This study is to evaluate the feasibility of transnasal esophagogastroduodenoscopy in the diagnosis of UGI disorders at the same time as the diagnosis of hypopharyngeal cancer and to provide the prevalence of UGI disorders in patients with fresh hypopharyngeal cancer. Study Design: A prospective cases series study. Methods: Patients with newly diagnosed hypopharyngeal cancer between 2007 and 2010 were enrolled. An endoscope (GIF-XP260N; Olympus Optical, Tokyo, Japan) without conscious sedation was transnasally used to evaluate from the pharynx to duodenum. Results: One hundred two patients were evaluated. Sixty-five patients had at least one UGI disorder: gastric/duodenal ulcers in 32; active Helicobacter pylori infection in 36; and erosive esophagitis in 20 patients, including Los Angeles classification grade A in eight patients, grade B in 10, grade C in one, and grade D in one. Of the abovementioned disorders, 45 patients had only one, 17 patients had two, and three patients had all of the above disorders. Neither age, sex, location, nor T classification of the hypopharyngeal tumor was associated with the presence of UGI disorders. Conclusions: Transnasal esophagogastroduodenoscopy can be a single procedure to diagnose hypopharyngeal cancer and UGI disorders at one session. Approximately of the patients with fresh hypopharyngeal cancer had either erosive esophagitis, active H. pylori infection, or gastric/duodenal ulcers. Copyright ? 2013 The American Laryngological, Rhinological, and Otological Society, Inc.
SDGs

[SDGs]SDG3

Other Subjects
adult; age distribution; aged; article; cancer classification; conscious sedation; diagnostic accuracy; diagnostic value; digestive system disease; disease association; disease classification; duodenum; duodenum ulcer; endoscope; esophagogastroduodenoscopy; feasibility study; female; Helicobacter infection; human; hypopharynx cancer; major clinical study; male; pharynx; priority journal; prospective study; reflux esophagitis; sex difference; stomach ulcer; transnasal esophagogastroduodenoscopy; upper gastrointestinal non neoplastic disorder; Adult; Aged; Aged, 80 and over; Endoscopy, Digestive System; Feasibility Studies; Female; Gastrointestinal Diseases; Humans; Hypopharyngeal Neoplasms; Male; Middle Aged; Upper Gastrointestinal Tract
Type
journal article

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