Labeling enhancement of hydrophilic and hydrophobic molecules in tissue sections
Journal
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Journal Volume
11648
Date Issued
2021
Author(s)
Abstract
In this study, the efficiency of uni- and bi-directional molecular diffusion in porcine liver tissue sections was studied. Tissue sections on the order of a few hundred microns in thickness were used. We found that bi-directional diffusion is more efficient in delivering probe molecules. Therefore, bi-directional labeling is useful in visualizing tissue architecture in three-dimensions. ? 2021 SPIE. All rights reserved.
Subjects
Diffusion; Enhanced labeling; Multiphoton imaging; Tissue sections; Molecules; Bi-directional; Hydrophilic and hydrophobic; Liver tissue; Molecular diffusion; Probe molecules; Three dimensions; Tissue architecture; Tissue sections; Tissue
Type
conference paper