Approaching particle deposition separation characteristics in the Empty Nose Syndrome (ENS) nasal cavities with CT image-based nasal cavity and CFD-DPM simulations
Journal
Powder Technology
Journal Volume
458
Start Page
120954
ISSN
0032-5910
Date Issued
2025-05-31
Author(s)
Abstract
Particle deposition separations in a one-sided Empty Nose Syndrome (ENS) nasal cavity, before and after implant surgeries, are studied using CFD-DPM modeling in a computed tomography image-based nasal cavity geometry. PM10 deposition fraction simulation results after implant surgery are in good quantitative agreement with the previous measurements from healthy individuals. Compared to about half of the 20 μm particles that are separated by the nasal cavity during an inhalation period, the cumulative deposition fraction of 1 μm particles is only 7.0% and 6.4% for the healthy side and ENS side, respectively, before surgery. While 10 and 20 μm particles primarily deposit in the anterior part of the middle turbinate in the healthy side before surgery, delayed deposition is observed in the posterior part of the nasal cavity in the ENS diseased side. The delayed deposition is attributed to the presence of low-velocity vortices at the inferior turbinate, allowing the particles to take a longer time to be captured. After the submucosal implant surgery, PM10 particle deposition improves in the ENS side owing to the reduced vortex intensity and enlarged surface area, and in the healthy side owing to the balanced volumetric air flow rates between the two sides of the cavity.
Subjects
CFD-DPM
Empty nose syndrome (ENS)
Nasal cavity
Particle deposition
Submucosal implant surgery
SDGs
Publisher
Elsevier BV
Type
journal article