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Leptin interferes with adrenocorticotropin/3′,5′-cyclic adenosine monophosphate (cAMP) signaling, possibly through a Janus kinase 2-phosphatidylinositol 3-kinase/Akt-phosphodiesterase 3-cAMP pathway, to down-regulate cholesterol side-chain cleavage cytochrome P450 enzyme in human adrenocortical NCI-H295 cell line
Journal
Journal of Clinical Endocrinology and Metabolism
Journal Volume
91
Journal Issue
7
Pages
2761-2769
Date Issued
2006
Author(s)
Type
journal article