Oligonorbornenes with hammock-like crown ether pendants as artificial transmembrane ion channel
Journal
Chemistry - An Asian Journal
Journal Volume
8
Journal Issue
7
Pages
1436-1440
Date Issued
2013
Author(s)
Abstract
Abstract Trimeric oligonorbornenes with hammock‐like crown ether pendants 3b and 3c were selectively synthesized by cascade metathetical cyclopolymerization upon treatment with the first generation Grubbs catalyst. These crown‐ether‐containing oligonorbornenes are impregnated in egg yolk phosphatidylcholine (EYPC) liposome as an artificial ion channel. The efficiency of the sodium ion transport properties has been examined. Oligomer 3c having a polar hydroxy end group exhibits the highest transport efficiency, which is comparable with the best efficiencies reported in literature. The orientation of the crown ether moieties in these oligomers may be critical for the ion transport properties.
SDGs
Type
journal article