Sequence-selective peptide detection by small synthetic chemosensors selected from an encoded combinatorial chemosensor library
Journal
Bioorganic and Medicinal Chemistry Letters
Journal Volume
11
Journal Issue
13
Pages
1635-1638
Date Issued
2001
Author(s)
Abstract
Synthetic chemosensors hold great potential in many diagnostic applications. In this study, we describe the design and preparation of the first encoded combinatorial library of chemosensors for tripeptides. Subsequent screening of the library resulted in the discovery of novel chemosensors able to distinguish between random tripeptides.
Type
journal article