A cell-permeable and triazole-forming fluorescent probe for glycoconjugate imaging in live cells
Journal
Chemical Communications
Journal Volume
53
Journal Issue
9
Pages
1490-1493
Date Issued
2017
Author(s)
Abstract
A new fluorescence-forming probe, coumOCT, designed by fusing cyclooctyne with a coumarin fluorophore was successfully used for the imaging of azido-glycoconjugates in living HeLa cells. This probe is cell-permeable and generates fluorescence after triazole formation, thus minimizing the background signal and enabling the real-time intracellular imaging of glycoconjugate trafficking.
SDGs
Type
journal article