Complex genomic variants contribute toward the genetic architecture of autism spectrum disorder
Journal
Psychiatric genetics
Journal Volume
26
Journal Issue
2
Pages
95-96
Date Issued
2016
Author(s)
Abstract
Genetic factor plays a critical role in the etiology of autism spectrum disorder (ASD). Both common variants with a small effect and rare mutations with a large effect contribute toward the genetic basis of ASD, showing the high genetic heterogeneity of ASD. Genomic rearrangements account for around 10-15% of its genetic landscape. However, they are highly individualized and each of them has a very rare frequency.
SDGs
Type
journal article