2026 Expert Consensus Recommendations on Hypertrophic Cardiomyopathy: A Report of the Task Force of the Taiwan Society of Cardiology.
Journal
Acta Cardiologica Sinica
Journal Volume
42
Journal Issue
3
Pages
296 - 338
ISSN
1011-6842
Date Issued
2026-05
Author(s)
Hung, Chung-Lieh
Wu, Yen-Wen
Lai, Chih-Hung
Chen, Mei-Ling
Liang, Hsin-Yueh
Kuo, Ling
Wang, Chun-Li
Liu, Yen-Wen
Tsai, Wei-Chuan
Chang, Hung-Yu
Chang, Wei-Ting
Chen, Po-Sheng
Hsieh, I-Chang
Yu, Wen-Chung
Li, Yi-Heng
Abstract
Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease worldwide. However, only a small percentage of cases are diagnosed clinically, suggesting under-recognition, with most clinicians exposed to small segments of the broad disease spectrum, in which effort intolerance, heart failure, arrhythmias, and sudden cardiac death can occur. Comprehensive evaluations and longitudinal assessments with echocardiography, ambulatory electrocardiography, stress testing, and, in some cases, cardiac magnetic resonance imaging, are important for diagnosis, risk stratification, distinguishing obstructive from nonobstructive forms, and guiding therapy. Symptomatic patients can be treated with various medications, including a new class of cardiac myosin inhibitors. For patients whose symptoms do not respond to medical therapy or in whom medical therapy is not desired, invasive septal reduction therapy options, when performed at expert centers, have been shown to lead to successful outcomes. The Taiwan Society of Cardiology recently appointed a task force to formulate a consensus on HCM. Based on the most up-to-date information, the consensus emphasizes a comprehensive diagnostic approach, including imaging and genetic testing, family screening and risk assessment, and provides current evidence-based important recommendations to guide clinicians in the management of patients with HCM.
Subjects
Cardiac magnetic resonance imaging
Cardiac myosin inhibitors
Echocardiography
Family screening
Hypertrophic cardiomyopathy
Risk stratification
Sarcomeric genes
Septal reduction therapy
Sudden cardiac death
Taiwan
Type
journal article