Outcome and Subsequent Pregnancy after Fertility-Sparing Surgery of Early-Stage Cervical Cancers
Journal
International journal of environmental research and public health
Journal Volume
17
Journal Issue
19
Date Issued
2020
Author(s)
Abstract
We aimed to investigate the outcomes and subsequent pregnancies of early-stage cervical cancer patients who received conservative fertility-sparing surgery. Women with early-stage cervical cancer who underwent conservative or fertility-sparing surgery in a tertiary medical center were reviewed from 2004 to 2017. Each patient's clinicopathologic characteristics, adjuvant therapy, subsequent pregnancy, and outcome were recorded. There were 32 women recruited, including 12 stage IA1 patients and 20 stage IB1 patients. Twenty-two patients received conization/LEEP and the other 10 patients received radical trachelectomy. Two patients did not complete the definite treatment after fertility-sparing surgery. There were 11 women who had subsequent pregnancies and nine had at least one live birth. The live birth rate was 73.3% (11/15). We conclude that patients with early-stage cervical cancer who undergo fertility-sparing surgery can have a successful pregnancy and delivery. However, patients must receive a detailed consultation before surgery and undergo definitive treatment, if indicated, and regular postoperative surveillance.
Subjects
cervical cancer; conization; fertility-sparing surgery; pregnancy; radical trachelectomy
Cervical cancer; Conization; Fertility-sparing surgery; Pregnancy; Radical trachelectomy
SDGs
Other Subjects
cancer; fertility; pathology; pregnancy; womens health; adult; Article; birth rate; cancer adjuvant therapy; cancer staging; cancer surgery; cervicectomy; clinical article; clinical feature; consultation; controlled study; disease surveillance; early cancer; female; female fertility; fertility sparing surgery; human; human tissue; live birth; loop electrosurgical excision procedure; obstetric delivery; outcome assessment; postoperative care; pregnancy; retrospective study; tertiary health care; uterine cervix cancer; uterine cervix conization; uterus surgery; adolescent; cesarean section; newborn; pathology; pregnancy; pregnancy outcome; treatment outcome; uterine cervix tumor; Adolescent; Cesarean Section; Female; Humans; Infant, Newborn; Neoplasm Staging; Pregnancy; Pregnancy Outcome; Trachelectomy; Treatment Outcome; Uterine Cervical Neoplasms
Publisher
MDPI
Type
journal article