Biocompatibility of NbTaTiVZr with Surface Modifications for Osteoblasts
Journal
ACS Applied Bio Materials
Journal Volume
5
Journal Issue
2
Pages
642-649
Date Issued
2022
Author(s)
Lin S.-J.; Lin J.-A.; Yu W.; Lee C.; Hung C.-Y.; Poplawsky J.D.; Liaw P.K.; Chou Y.-C.
Abstract
We report a potential biomedical material, NbTaTiVZr, and the impact of surface roughness on the osteoblast culture and later behavior based on in vitro tests of preosteoblasts. Cell activities such as adhesion, viability, and typical protein activity on NbTaTiVZr showed comparable results with that of commercially pure Ti (CP-Ti). In addition, NbTaTiVZr with a smooth surface exhibits better cell adhesion, viability, and typical protein activity which shows that surface modification can improve the biocompatibility of NbTaTiVZr. This supports the biological evidence and shows that NbTaTiVZr can potentially be evaluated as a biomedical material for clinical use. © 2022 American Chemical Society
Subjects
Biomedical engineering; Cell adhesion; Proteins; Surface roughness; Behavior-based; Biomedical material; Cell activity; Cells adhesion; In-vitro tests; Osteoblast cultures; Preosteoblasts; Protein activity; Smooth surface; Surface-modification; Biocompatibility; biomaterial; titanium; cell adhesion; metabolism; osteoblast; surface property; Biocompatible Materials; Cell Adhesion; Osteoblasts; Surface Properties; Titanium
Publisher
American Chemical Society
Type
journal article