Diversity and composition of gut microbiota in healthy individuals and patients at different stages of hepatitis B virus-related liver disease
Journal
Gut pathogens
Journal Volume
15
Journal Issue
1
Pages
24
Date Issued
2023-05-22
Abstract
Hepatitis B virus (HBV) causes chronic hepatitis B (CHB), liver cirrhosis, and hepatocellular carcinoma. The evolution of human gut microbiota during the progression of HBV-related liver diseases remains unclear. Therefore, we prospectively enrolled patients with HBV-related liver diseases and healthy individuals. Through 16S ribosomal RNA amplicon sequencing, we characterized the gut microbiota of the participants and predicted the functions of microbial communities.
Subjects
16S rRNA sequencing; Gut microbiota; Hepatitis B virus; Hepatocellular carcinoma; Liver cirrhosis; Metagenomics; Resolved hepatitis B virus infection
SDGs
Publisher
BMC
Type
journal article