Miller-Dieker Syndrome Associated with Tight Filum Terminale
Resource
PEDIATRIC NEUROLOGY v.34 n.3 pp.228-230
Journal
PEDIATRIC NEUROLOGY
Journal Volume
v.34
Journal Issue
n.3
Pages
228-230
Date Issued
2006
Date
2006
Author(s)
CHEN, SHEING-JYE
PENG, SHINN-FORNG
KUO, MENG-FAI
LEE, WANG-TSO
LIANG, CHAO-HSUAN
Abstract
An 8-year-old female was diagnosed with Miller-Dieker syndrome with typical facial presentation. Brain magnetic resonance imaging disclosed lissencephaly, and chromosome study revealed 17p13.3 deletion. She developed infantile spasms at an early age, and her seizures were poorly controlled by multiple antiepileptics. Recurrent urinary tract infections were diagnosed during routine out-patient department follow-up. Urodynamic study disclosed a neurogenic bladder. Spinal magnetic resonance imaging revealed a tethered cord resulting from tight filum terminale, and untethering surgery was performed. Four months after the surgery, repeated urine cultures indicated that she was free from the urinary tract infection. Urodynamic study after untethering surgery demonstrated improved compliance of the urinary bladder.
Subjects
CORD