Metabolomic analysis of platelets of patients with aspirin non-response
Journal
Frontiers in Pharmacology
Journal Volume
10
Pages
1107
Date Issued
2019
Author(s)
Lee S.-H.
Chen Y.-C.
Chuang J.-Y.
Yeh S.-F.
Hsu C.-A.
Lin B.-B.
Chang P.-C.
Chang C.-H.
Liang H.-J.
Abstract
The hydrophilic metabolic profile of platelets was not different between aspirin non-responders and responders. An association between lower glycine levels and higher platelet activity in patients younger than 65 years suggests an important role of glycine in the pathophysiology of aspirin non-response.
Type
journal article