Caffeic acid phenethyl ester inhibits the growth of bladder carcinoma cells by upregulating growth differentiation factor 15
Journal
Biomedical journal
Journal Volume
45
Journal Issue
5
Date Issued
2022-10
Author(s)
Hou, Chen-Pang
Tsui, Ke-Hung
Chang, Kang-Shuo
Sung, Hsin-Ching
Hsu, Shu-Yuan
Lin, Yu-Hsiang
Chen, Chien-Lun
Feng, Tsui-Hsia
Juang, Horng-Heng
Abstract
Caffeic acid phenethyl ester (CAPE), a bioactive component of propolis, has beneficial effects on cancer prevention. Growth differentiation factor 15 (GDF15) is an antitumor gene of bladder cancer. Therefore, this study investigated the anti-cancer effect of CAPE on bladder carcinoma cells and related mechanisms.
Subjects
AMPK; Bladder; CAPE; GDF15; MAPK; NDRG1
SDGs
Type
journal article