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  4. A CMOS Low-noise Analog Front-End IC Design for Biomedical Applications
 
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A CMOS Low-noise Analog Front-End IC Design for Biomedical Applications

Date Issued
2007
Date
2007
Author(s)
Pin, Hsu Yu
DOI
en-US
URI
http://ntur.lib.ntu.edu.tw//handle/246246/57602
Abstract
With the dramatic development of semiconductor technology in recent years, CMOS bio-sensors have been integrated with CMOS circuits, which make realization of CMOS biomedical SoC possible, leading to miniature and low cost biomedical systems. In addition, analog front-end with the function of signal arrangement is a critical component in the biomedical system. In this thesis, an instrumentation amplifier (IA), a new analog front-end (AFE) IC, and an automatic–gain control amplifier (AGC) based on the TSMC 0.35μm technology are proposed to realize high performance biomedical ICs. At first, through the use of chopper technique in the differential difference amplifier, the proposed IA attains a low offset of 2.5μV, a low input referred noise of 1nV/√HZ, a high gain of 59dB with 40KHZ bandwidth under the 1.55MHZ chopping while drawing 641μW from 3-V voltage supply. The die area is 0.96x0.94mm2. Furthermore, a brand new biomedical analog front-end is presented, and meets high performance using only an IA and a LPF. This AFE circuit not only attains high programmable gains of 58dB-80dB, a low offset of 31μV, a low input referred noise of 70 nV/√HZ, and high CMRR as well as PSRR but also provides rail-to-rail input common-mode range, high driving ability, and rail-to-rail output signal swing. The die area is 2.44 mm2 and the power consumption is 675μW from 3-V voltage supply. Finally, a novel CMOS feed-forward automatic-gain control (FFAGC) amplifier is presented. The proposed amplifier is intended to amplify various kinds of biomedical signals with a wide dynamic range characteristic. The feed-forward automatic-gain control (FFAGC) technique is adopted to provide appropriate gain settings. Furthermore, a class-AB output stage realizes large driving ability for an external ADC. The experimental results showed that variable gains of 0 dB, 6 dB, 14 dB, and 20 dB with a bandwidth of 55 kHz, input referred noise of 200nV/√HZ at 500 Hz, rail-to-rail input common-mode range, and rail-to-rail output dynamic range can be achieved while the output loading capacitor is 330 nF. The power consumption is 819 μW with 3 V of supply voltage.
Subjects
截波
差微差動放大器
類比前置電路
放大器
chopper
differential difference amplifier
analog front end
amplifier
Type
thesis
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