The beneficial effect on cognition of noninvasive brain stimulation intervention in patients with dementia: a network meta-analysis of randomized controlled trials
Journal
Alzheimer's research & therapy
Journal Volume
15
Journal Issue
1
Date Issued
2023-01-25
Author(s)
Tseng, Ping-Tao
Chen, Yen-Wen
Zeng, Bing-Yan
Zeng, Bing-Syuan
Hung, Chao-Ming
Sun, Cheuk-Kwan
Cheng, Yu-Shian
Stubbs, Brendon
Carvalho, Andre F
Brunoni, Andre R
Su, Kuan-Pin
Wu, Yi-Cheng
Chen, Tien-Yu
Lin, Pao-Yen
Liang, Chih-Sung
Hsu, Chih-Wei
Chu, Che-Sheng
Suen, Mein-Woei
Li, Cheng-Ta
Abstract
Dementia [i.e., Alzheimer disease (AD)], the most common neurodegenerative disease, causes profound negative impacts on executive function and quality of life. Available pharmacological treatments often fail to achieve satisfactory outcomes. Noninvasive brain stimulation (NIBS) techniques, which focally modify cortical function and enhance synaptic long-term potentiation, are potentially beneficial for the cognition in patients with AD. The aim of the current network meta-analysis (NMA) was to evaluate the efficacy and safety of different NIBS interventions in patients with AD through NMA.
Subjects
Alzheimer’s disease; Cognition; Dementia; Neuropathology; Primary care
SDGs
Publisher
BMC
Type
journal article