Recent advances in nanoparticle-based förster resonance energy transfer for biosensing, molecular imaging and drug release profiling
Journal
International Journal of Molecular Sciences
Journal Volume
13
Journal Issue
12
Pages
16598-16623
Date Issued
2012
Author(s)
Abstract
Förster resonance energy transfer (FRET) may be regarded as a "smart" technology in the design of fluorescence probes for biological sensing and imaging. Recently, a variety of nanoparticles that include quantum dots, gold nanoparticles, polymer, mesoporous silica nanoparticles and upconversion nanoparticles have been employed to modulate FRET. Researchers have developed a number of "visible" and "activatable" FRET probes sensitive to specific changes in the biological environment that are especially attractive from the biomedical point of view. This article reviews recent progress in bringing these nanoparticle-modulated energy transfer schemes to fruition for applications in biosensing, molecular imaging and drug delivery.
SDGs
Type
journal article
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