Synchronized Tracking of Respiration-Induced Liver Tumor Motion by Ultrasound Imaging
Date Issued
2012
Date
2012
Author(s)
Tsai, Ming-Hsien
Abstract
In recent studies, magnetic resonance image-guided high intensity focused ultrasound thermotherapy system has been proposed for the static tumors such as breast tumors and uterine fibroid tumors. However, it is very difficult to achieve real-time tracking thermotherapy by magnetic resonance image in mobile tumors, such as liver tumors and lung tumors. It is because the frame rate of the magnetic resonance image is only 7 Hz, which is not sufficient for real-time tracking.
Therefore, this study is aimed at developing an ultrasound image-guided synchronization system. It can be applied to ultrasound image-guided high intensity focused ultrasound thermotherapy system for liver tumor. Compare to the magnetic resonance image, the ultrasound image has the advantage of high speed, low cost, and no harm to human body. However, ultrasound image has the shortage of slice thickness effect. This study bases on the characteristics of liver movement, and proposes the alignment and synchronization methods to reduce the slice thickness effect of ultrasound image. In order to realize the proposed alignment and synchronization methods, the six degree of freedom robot arm is built on the therapeutic system. The six degree of freedom robot arm is built based on the size and the movement of human liver. The alignment and synchronization experiments are done under the plastic ball experiments. The average alignment error is 1.2 degree and 0.4 mm. The synchronization errors are below 1.24 mm. It is believed that this study can apply to the real-time ultrasound image-guided high intensity focused ultrasound thermotherapy system for liver tumors.
Subjects
ultrasound image-guided system
liver tumor treatment
synchronization
alignment
Type
thesis
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