The role of surgery in the management of primary gastric lymphoma
Journal
Journal of Surgical Association Republic of China
Journal Volume
26
Journal Issue
2
Pages
1662-1669
Date Issued
1993
Author(s)
Abstract
With progress in chemotherapy regimens and radiotherapy techniques, the treatment of primary gastric lymphoma (PGL) has evolved to become multimodal therapy, and the role of surgery has been reappraised. A total of 97 cases of gastric lymphoma were reviewed from 1977 to 1991 at NTUH. Ninety-two of those were followed up and managed by Kaplan-Meier product-limit survival analysis. The treatment modalities included surgery (S), chemotherapy (C), chemotherapy + surgery (C+S), radiation + chemotherapy (R+C), and surgery + radiation + chemotherapy (S+R+C). The median survival time was 53.0, 47.0, and 33.0 months, respectively, for patients with stage I E (n = 31), II E (n = 24), and III E + IV E (n = 37). The results for stage I E, II E and III E + IV E cases who received resection therapy were significantly improved (P < 0.05) over the non-resected cases. It was concluded that an aggressive surgical approach to the treatment of PGL is still warranted.
SDGs
Other Subjects
antineoplastic agent; bleomycin; chlormethine; cyclophosphamide; doxorubicin; etoposide; methotrexate; prednisone; procarbazine; vincristine; article; clinical article; human; lymphoma; stomach cancer; survival
Type
journal article