Sinugibberosides A-E, new terpenoids with cyclic peroxyhemiketal from the soft coral Sinularia gibberosa
Journal
Tetrahedron
Journal Volume
62
Journal Issue
29
Pages
6802-6807
Date Issued
2006
Author(s)
Abstract
The organic extract of the soft coral Sinularia gibberosa, collected from the northern Taiwan, has been investigated and resulted in the isolation of five new xeniaphyllane-type diterpenoids with a rare cyclic peroxyhemiketal (3,6-dihydro-1,2-dioxin-3-ol) moiety, sinugibberosides A-E (1-5). The structures of the new terpenoids, including their stereochemistries, were established on the basis of extensive spectroscopic analysis, including 1D and 2D NMR (1H-1H COSY, HMQC, HMBC, and NOESY), and by comparison of their NMR data with those of related compounds. Metabolites 1-5 represent the first example of marine terpenoids possessing a cyclic peroxyhemiketal moiety. © 2006 Elsevier Ltd. All rights reserved.
SDGs
Type
journal article