A novel 3,4-secocycloartane triterpene, bearing a tetrahydropyran moiety, from pasania formosana leaf
Journal
Natural Product Communications
Journal Volume
11
Journal Issue
8
Pages
1079-1080
Date Issued
2016
Author(s)
Abstract
Bioassay guided fractionation against ?-glucosidase and separation of the ethanolic extract of Pasania formosana leaf by chromatographic methods led to the isolation of a novel secocycloartane triterpene. This compound, named pasasecocycloartenoic acid, was elucidated as 21,24(R)-epoxy-25-hydroxy-3,4-secocycloart-4(28)-en-3-oic acid through analysis of 1D and 2D NMR spectra and on the basis of HRESIMS data. The compound showed weak activity against ?-glucosidase, but its poor solubility hampered the bioassay.
Type
journal article