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Myasthenia gravis with superimposed spinal cord injury: A case report

Journal
Journal of Rehabilitation Medicine
Journal Volume
40
Journal Issue
8
Pages
684-686
Date Issued
2008
Author(s)
Lin C.-S.
Wang J.-H.
Wang Y.-H.
SHIN-LIANG PAN  
DOI
10.2340/16501977-0222
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-53349102618&doi=10.2340%2f16501977-0222&partnerID=40&md5=35e08fea578ac6df9201875c5d631dcf
https://scholars.lib.ntu.edu.tw/handle/123456789/482896
Abstract
Both myasthenia gravis and traumatic spinal cord injury are uncommon disorders and their concurrence is extremely rare. We report here the case of a man with stable myasthenia gravis with spinal cord injury due to a motor vehicle accident. His muscle strength and sensory function in all 4 limbs partially recovered during the initial hospitalization. However, after a later episode of pneumonia and urinary tract infection, muscle strength deteriorated and weakness of the ocular muscles occurred. A relapse of myasthenia gravis was confirmed by the elevated anti-acetylcholine receptor antibody titre. Muscle strength recovered rapidly after control of infection and treatment of myasthenia gravis exacerbation. In this case report, we show that spinal cord injury-related complications, including infection or emotional stress, could trigger a relapse of myasthenia gravis. This highlights the importance of recognizing an exacerbation of myasthenia gravis in spinal cord injury patients with a history of myasthenia gravis, since they are prone to urinary and pulmonary infection. Although exacerbation of myasthenia gravis might prolong hospitalization, the functional outcome of spinal cord injury might not be affected if the exacerbation is diagnosed and treated quickly. ? 2008 The Authors. Journal Compilation ? 2008 Foundation of Rehabilitation Information.
SDGs

[SDGs]SDG3

Other Subjects
antibiotic agent; cholinergic receptor antibody; corticosteroid; methylprednisolone; pyridostigmine; adult; antibody titer; article; bladder training; case report; cervical spinal cord injury; diplopia; drug megadose; dysphagia; electromyography; human; laminectomy; limb weakness; male; myasthenia gravis; nerve stimulation; nuclear magnetic resonance imaging; paresthesia; plasmapheresis; ptosis; quadriplegia; reflex disorder; rehabilitation care; relapse; respiratory tract infection; spasticity; spinal cord decompression; spine stabilization; thymectomy; traffic accident; urinary tract infection; urine retention; Accidents, Traffic; Humans; Male; Middle Aged; Muscle Strength; Myasthenia Gravis; Spinal Cord Injuries; Treatment Outcome
Type
journal article

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