Automated delineation of calcified vessels in mammography by tracking with uncertainty and graphical linking techniques
Journal
IEEE Transactions on Medical Imaging
Journal Volume
31
Journal Issue
11
Pages
2143-2155
Date Issued
2012
Author(s)
Abstract
As a potential biomarker for women's cardiovascular and chronic kidney diseases, breast arterial calcification (BAC) in mammography has become an emerging research topic in recent years. To provide more objective measurement for vascular structures with calcium depositions in mammography, a new computerized method is introduced in this paper to delineate the calcified vessels. Specifically, we leverage two underlying cues, namely calcification and vesselness, into a multiple seeded tracking with uncertainty scheme. This new vessel-tracking scheme generates plenty of sampling paths to describe the complicated topology of the vascular structures with calcium depositions. A compiling and linking process is further carried out to organize the sampling paths together to be the vessel segments that likely belong to the same vessel tract. The proposed method has been evaluated on 63 mammograms, by comparison with manual delineations from two experts using various assessment metrics. The experiment results confirm the efficacy and stability of the proposed method, and also indicate that the proposed method can be potentially used as a convenient BAC measurement tool in replacement of the trivial and tedious manual delineation tasks. ? 1982-2012 IEEE.
Subjects
Breast arterial calcification (BAC); curve linking; mammography; uncertainty; vessel tracking
SDGs
Other Subjects
Breast arterial calcification (BAC); Chronic kidney disease; Computerized methods; curve linking; Objective measurement; uncertainty; Vascular structures; Vessel tracking; Biomineralization; Bone; Calcium; Deposition; Mammography; Measurements; algorithm; article; breast; breast disease; calcinosis; computer assisted diagnosis; female; human; mammography; methodology; pathology; radiography; vascularization; breast disease; calcinosis; computer assisted diagnosis; mammography; procedures; radiography; Algorithms; Breast; Breast Diseases; Calcinosis; Female; Humans; Mammography; Radiographic Image Interpretation, Computer-Assisted; Algorithms; Breast; Breast Diseases; Calcinosis; Female; Humans; Mammography; Radiographic Image Interpretation, Computer-Assisted
Type
journal article