Assessing causality between childhood adiposity and early puberty: A bidirectional Mendelian randomization and longitudinal study
Journal
Metabolism: clinical and experimental
Journal Volume
100
Date Issued
2019
Author(s)
Abstract
Obesity and early puberty have been reported to be mutually causative. We investigated the causal relationship between adiposity and early puberty by performing bidirectional Mendelian randomization (MR) and longitudinal data analyses.
Subjects
Causality; Early puberty; Longitudinal study; Mendelian randomization analysis; Overweight
SDGs
Other Subjects
adolescent; Article; body composition; body mass; causality; child; childhood obesity; cohort analysis; fat free mass; female; follow up; human; longitudinal study; male; menarche; Mendelian randomization analysis; obesity; priority journal; puberty; school child; sensitivity analysis; single nucleotide polymorphism; survival analysis; causality; childhood obesity; Mendelian randomization analysis; obesity; Adiposity; Adolescent; Causality; Child; Female; Humans; Longitudinal Studies; Male; Mendelian Randomization Analysis; Pediatric Obesity; Puberty
Publisher
W B SAUNDERS CO-ELSEVIER INC
Type
journal article